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What kind of app is this? Web or desktop?
If it is a web app then hosting it in the cloud will certainly allow people to access it, however handling purchasing and access would be something the application would need to deal with.
If your question is about something else then if you could provide more detail someone might be able to offer a bit more specific advice.
If it is a desktop application then they are still likely to need to install the application locally, you could certainly share the installer out from the cloud but that isn't the same thing as running it from the cloud.
If you didn't want the customers to install the application locally you could provide a virtual machine in the cloud that they connect to using RDP, however this could work out very expensive depending on the size, number and up time of the the virtual machines in question.